Prediction of aggressive surgeries during maximal tumor cytoreduction in advanced ovarian epithelial cancer

Liu Fenghua; Xu Chunmiao; Wang Gangcheng; Zhou Jinxue; Wang Liying

doi:10.3969/j.issn.1004-437X.2015.06.003

Abstract：Objective To study the value of prediction of aggressive surgeries in maximal tumor cytoreduction based on CT images analyzed by multidisciplinary doctors in patients with advanced ovarian cancer. Methods The data of clinic and surgery were collected in 60 cases with stageⅢC~Ⅳovarian cancer. All CT scan images were analyzed by multi-displinary doctors. Prediction of tumor leisions and corresponding aggressive surgeries were recorded one by one in 14 difficulted cytoreductive re-gions including surface of diaphragm and hepatic capsule,hepatic hilum,hepatorenal recess,liver parenchyma,splenic paren-chyma,perisplenic fascia,colic splenic flexure,colic hepatic flexcure,transvers colon,ileoceacal junction,rectosigmoid colon, large or high level lymph node retroperitoneum,pelvic peritoneal and root of intestinal mesentery. Results According to surgical fingings,the accuracy of CT prediction for lesions in the 14 regions were 100. 0%,93. 3%,81. 7%,100. 0%,100. 0%, 90. 0%,85. 0%,76. 7%,83. 3%,96. 0%,88. 3%,93. 3%,98. 3% and 86. 7% respectively. According to 77 times ag-gressive surgeries in 42 cases with optimal tumor cytoreduction,the sensibility of CT prediction in former 13 regions were attained to 100. 0% apart from that in region of rectosigmoid and pelvic peritoneal were 80. 0% and 85. 7% respectively. Conclusion CT prediction for aggressive surgeries in maximal tumor cytoreductive surgery is very sensitive,which means that assessing maxi-mal surgical risk become capable and reliable. The new style of prediction seems better in meeting clincal practice in advanced o-varian cancer,and may be a new approach to assess optimal cytoreduction before surgery in future.