Efficacy of low -dose domestic clopidogrel in the treatment of patients with transient ischemic attack over 70 years old
Zhao Qiankang
Abstract：Objective To study the efficacy and safety of low -dose domestic clopidogrel in the treatment of patients with transient ischemic attack over 70 years old.Methods 176 patients with transient ischemic attack over 70 years old were selected and randomly divided into treatment group (low -dose domestic clopidogrel,89 cases)and control group (imported clopidogrel,87 cases).The ini-tial doses of clopidogrel in both two groups were 75 mg/d.The dose of low -dose domestic clopidogrel was adjusted to 50 mg/d after 14 days’treatment.Two groups were treated for 3 months.The curative effect and adverse reactions in two groups were observed.Results The effective rates of treatment group and control group were 65.17% and 66.67%,and the difference was not statistically significant (P >0.05).There was no patient with obvious bleeding tendency and gastrointestinal reaction in the course of treatment in the two groups.Conclusion Low -dose domestic clopidogrel had a good efficacy and high safety in the treatment of patients with transient is-chemic attack over 70 years old,same as imported clopidogrel.It deserves the clinical expansion.
Keywords：clopidogreltransient ischemic attackcurative effect
Publication Date：2015-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：2( 27-28 )