Clinical efficacy of cytokine -indcued killer cells in the treatment of melanoma with liver metastasis
Zhang Yong
Wang Zibing
Zhao Lingdi
Li Wei
Fu Xiaomin
Wang Li
Gao Quanli
Abstract：Objective To explore the clinical efficacy of cytokine -indcued killer cells in the treatment of melanoma with liv-er metastasis.Methods Ten patients with melanoma accompanied by liver metastasis were selected and received the therapy with CIK cells.Except for the transfusion of CIK cells,the patients received the therapy with interleukin -2 and thymopeptides. Fifteen to twenty days were one cycle and the efficacy was evaluated by RECIST criterion.Results There was no patient who gained remission,but 8 cases gained stable diseases and the disease control rate was 80%(8 /1 0).The median time to progres-sion was three months(1 ~1 1 months)and the median survival time was 4.5 months(1 ~1 3 months).The side -effects were mild.Conclusion CIK is an effective regimen for melanoma patients with liver metastasis.
Keywords：cytokine -induced killer cellsmelanomaliver metastasis
Publication Date：2015-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：3( 15-17 )