Clinical analysis of low-dose amiodarone therapy in the management of ventricular arrhythmias
WANG Zhen
Abstract：Objective：To evaluate the efficacy and safety of low-dose amiodarone therapy in the management of ventricular arrhythmias.Methods：56 patients with symptomatic drug refractory managed with low-dose oral amiodarone therapy over 5-year period was analyzed retrospec tively. Loading dose of amiodarone 800 mg daily for 1 week, 400 mg daily for anoth er week, then, 100-200 mg daily as maintenance daily.Mean treatment duration was 29±8 months.Results：The efficacy of amiodarone was 81% in the management of ventricular arrhymias. The cumulative incidence of amiodarone related adverse effects was 9%. 1 patient had thyroid dysfunction, and 1 developed pulmonary int erstitial fibrosis.Conclusion：The higer efficacy and acceptable side effect profile of low amiodarone therapy in the management of ventricular arrhythmias.
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Publication Date：2001-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：2( 151-152 )