Clinical effects of urokinase-heparin serial thrombolytic th erapy on patients with unstable angina
Abstract：Objective：That a comparison of between urokinase (UK)-heparin serial thrombolytic therapy and conventional therapy affected patients with unstable angina (UA) probed into a reasonable UA treatment program by use of UK.Methods：Adopted the randomized placebo-controlled method,the patients with UA were divided into thrombolytic group (TLG) and control group (C G),and recent recurrence rate and degree of severity of UA,ECG change of both groups ,and the rate of re-hospitalization and that of turning into stable angina were studied.Results：Total 92 patients with UA (divided equally into two gr oups) were enrolled.The results indicated there were no differences in HR,BP and other vital signs and no extra cardiac oxygen uptake needed of TLG between before and after thrombolytic treatment (all P＞0.05)，but anti-angina effects of thrombolytic therapy are obviously better than CG in terms of lessening of r ecurrence times,shorting of lasting time,alleviating of suffering and lowered ST segment (P＜0．05～0．01）,and reducting of the rates of accompanying by ventricular premature beats,tachycardias and re-hospitalization.Con clusion: The thrombolytic therapy program of low dosage and slow medicat ion of UK combined with heparin fit for treatment of UA.
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Publication Date：2001-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：3( 125-127 )