Clinical valuation of liporotein(a) in evalued left atrial thrombus of patients with chronic atrial fibrillation
Abstract：Objective： To explore the valutation of Lp(a) for left atrial thrombus in patients with chronic atrial fibrillation.Methods： 62 patients with chronic atrial fibrillation underwent transesophageal echocardiography(TEE) or mitral valve replacement surgery to detect left atrial thrombus,measure serum concentration of lipoprotein(a),D-dimer,Plasminogen activity level etc,analysing their result contrastively.Results： (1)Left atrial thrombus was significantly more frequency in the high-Lp(a) group(56%) than in the low-Lp(a) group(13%) (P=0.0013).(2)There are 28 patients with spontaneous echo contrast(SEC) of left atrium≥2 grade in the 45 patients detected by TEE,left artial thrombus were present in 5(100%) of 5 patiens with high-Lp(a) and SEC.left atrial thrombus were present in 4(17%) of 23 patiens with low-Lp(a) and SEC (P=0.00135).(3)The levels of Lp(a) and D-Dimer were highter in the patients with left atrial thrombus than the patients without left atrial thrombus.Conclusion: Elevated serum levels of Lp(a) relate to thrombosis and it is a risk factor for left atrial thrombosis in patiens with chronic atrial fibrillation.
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Publication Date：2001-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：3( 45-47 )