Study of expression of placental glutathione S-transferase in laryngeal tumors
Abstract：Objective: The experiment is to study the expression of glutathione S-transferase (GST-π) in laryngeal tumors,suchas squamous cell cancer,papilloma and polyp. Methods: Expression of GST-π was studied immunohistochemically(glue-goldmethod) in routinely processed tissues from 34 eases of squamous cell cancer,31 cases of papilloma,38 cases of polyp of vocalcard. Results: The expression rates of GST-π in squamous cell cancer were 100%. The expression of GST-π in 3 eases ofsquamous cell cancer got stranger after chemical therapy. The expression rates of GST-π in papilloma were 12.9% but thestaining were light. All the larynx polyps were negative for GST-π. Conclusion: GST-π has the important significance for distinguishing benign and malignant tumors and producing chemotherapeutic resistance.
Keywords：glutathione S-transferase(GST-π)larynxtumor
Publication Date：2000-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：2( 137-138 )