Effect of Resveratrol on Reproductive Performance,Lactation Performance of Sows,and Antioxidant Capacity and Immunity of Piglets

LÜ Lingyan; SHI Yun; YAO Ling; LIU Zheng; HU Chuanhuo; YUAN Peng; ZHANG Jiaqing

doi:10.15933/j.cnki.1004-3268.2026.02.015

Abstract：To explore the effects of resveratrol on reproductive performance,lactation performance of sows and immunity of piglets,48 healthy sows with the same parity in the late pregnancy stage were selected and randomly divided into 4 groups(12 sows per group).The experimental period lasted from 7 days before delivery to 21 days after delivery.The control group was fed a basal diet,while the experimental groups were fed the basal diet supplemented with 100,200,and 300 mg/kg resveratrol(Resv-1,Resv-2,and Resv-3 groups),respectively.The results showed that in terms of reproductive performance,compared with the control group,Resv-2 and Resv-3 significantly increased the number of live births by 12.67%and 12.31%,respectively,the number of healthy piglets by 14.57%and 13.53%,respectively,the litter birth weight by 14.31%and 11.88%,respectively,and decreased the number of stillbirths by 49.70%and 51.52%,respectively.In terms of lactation performance,compared with the control group,the milk fat rate of Resv-2 and Resv-3 groups was significantly increased by 5.91%and 6.12%,respectively,the milk protein rate was significantly increased by 18.61%and 18.30%,respectively,and the non-fat solid content was significantly increased by 15.09%and 15.30%,respectively.Urea nitrogen content was significantly decreased 31.51%and 31.19%,respectively.For immunoglobulin content,compared with the control group,the IgG content of Resv-2 and Resv-3 groups was significantly increased by 10.14%and 8.74%in sows,and significantly increased by 25.03%and 24.22%in piglets,respectively.In terms of antioxidant capacity,compared with the control group,the glutathione peroxidase activity of piglets in Resv-2 and Resv-3 groups increased significantly by 25.80%and 22.67%,respectively,the superoxide dismutase activity increased significantly by 23.40%and 21.47%,respectively,the total antioxidant capacity increased significantly by 41.05%and 43.16%,respectively,and the malondialdehyde content decreased significantly by 24.70%and 23.36%,respectively.In terms of inflammatory factors,compared with the control group,the serum IL-1β levels of piglets in Resv-2 and Resv-3 groups were significantly reduced by 13.96%and 15.08%,respectively.The IL-6 was significantly reduced by 20.52%and 19.71%,respectively.The TNF-α was significantly reduced by 16.31%and 20.31%,respectively,and the IL-10 content was significantly increased by 35.22%and 35.52%,respectively.In conclusion,dietary supplementation of resveratrol for late pregnancy and lactation sows can improve their reproductive and lactation performance,enhance the antioxidant capacity and immunity of piglets,among which the supplementation levels of 200 mg/kg and 300 mg/kg exhibit relatively significant effects.