Research Progress on IL-33/ST2 Pathway and Its Relationship with Fat Metabolism
XIAO Rong
LI Jun
LI Chengping
GUO Yan
XIN Youzhi
ZHANG Haiyan
ZHOU Guoli
Abstract：Intramuscular fat(IMF) is an important indicator of meat quality, which can affect the tenderness and flavor of meat.Adipocyte differentiation is a complex network system regulated by multiple cytokines or pathways.IL-33/ST2 pathway is an important signaling pathway for regulating fat metabolism in recent years.This article mainly summarizes the research progress of ST2 variants and its regulation in IL-33/ST2 pathway, IL-33 interaction with ST2, effects and mechanism of IL-33/ST2 pathway onbeiging of white adipose, brown or beige adipose thermogenesis regulating.The purpose of this review is to provide a reference for the research on the mechanism of adipocyte differentiation and fat deposition.
Keywords：IL-33/ST2 pathwayWhite adiposeBrown adiposeRegulatory mechanism
Publication Date：2018-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：6( 1-6 )