Establishment of Optimization and Quality Control Method of Matrix Prescription for"Qiangjin Zhuanggu Zhufeng"Gel Pat-ches
SHI Qiongzhi
LIU Yang
LONG Zechun
ZHAO Qinqin
LIU Hui
Abstract：Objective To optimize the matrix prescription of"Qiangjin Zhuanggu Zhufeng"Gel Patches,establish the quality control method for the formula.Methods The dosage of glycerol,sodium polyacrylate NP700,tartaric acid and aluminum glycinate were used as influencing factors,and the comprehensive sensory score,initial adhesion force and holding adhesion force scores were measured,and the comprehensive score was calculated as the evaluation index,the Box-Behnken response surface method was used to optimize the matrix prescription of the Gel Patches.Results Optimal matrix prescription of"Qiangjin Zhuanggu Zhufeng"Gel Patches was 17.30 g of glycerol,2.50 g of sodium polyacrylate NP700,0.10 g of aluminum glycinate and 0.10 g of tartaric acid,the comprehensive score was 88.49 calculated by initial adhesion force,holding adhesion force and comprehensive sensory score.Conclusion After optimization,the resulting"QiangjinZhuanggu Zhufeng"Gel Patches has a uniformappearance and good performance,which meets the quality re-quirements of gel plasters.
Keywords："Qiangjin Zhuanggu Zhufeng"Gel PatchesOptimization of prescriptionResponse surface method
Publication Date：2025-12-28
Online Publishing Date：2026-01-31(First online date of this platform, not the publication date of the document)
Pages：8( 1025-1031,1037 )