Analysis of Risk Factors for Increased Drain Output After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases
YANG Lei
CHENG Le
CHEN Yongkang
SUN Chao
XIONG Chengjie
WEI Tanjun
CHEN Ying
XU Feng
Abstract：Objective To analyze the risk factors for increased drain output after transforaminal lumbar interbody fusion(TLIF)in patients with lumbar degenerative diseases.Methods 65 patients with lumbar degenerative diseases who underwent TLIF in author's hospital and had detailed drainage data from January 2020 to December 2022 were selected for retrospective study.Patients were divided into normal group(n=32)and increased group(n=33)based on the total drainage volume.The general data of the two groups were compared,and the risk factors of increased drainage flow after TLIF were determined by univariate analysis and multivariate Logistic regression analysis,the predictive value of relevant risk factors was analyzed by receiver operating characteristic(ROC)curves.Results The age,proportion of complica-tions,operation time,blood loss volume,preoperative D-dimer level and postoperative 1st day of drainage flow in the in-creased group were significantly higher than those in the normal group,while the levels of preoperative hemoglobin,post-operative albumin,preoperative white blood cell count and preoperative platelets were significantly lower than those in the normal group,the difference was statistically significant(all P＜0.05).Logistic regression analysis showed that intraop-erative blood loss and 1st day drainage volume were independent risk factors for increased drainage volume after TLIF(P＜0.05).The ROC curve analysis results showed that the area under the curve(AUC)of the combined prediction model of preoperative hemoglobin,blood loss and drain-age flow on the 1st day after surgery was 0.937,the sen-sitivity was 0.818,the specificity was 0.906,and the critical value was 0.59,the combined model predicted that the AUC of increased drainage volume after TLIF in patients with lumbar degenerative disease was higher than any single factor.Conclusion Intraoperative blood loss and postoperative drainage volume on the 1st day are independent risk factors for increased drainage volume after TLIF,and preoperative hemoglobin may be a protective factor for increased drainage volume.The regression model combined with blood loss,1st day drainage flow after surgery,and preoperative hemoglo-bin has high predictive value for the increase of drainage flow after TLIF in patients with lumbar degenerative diseases.
Keywords：Increased drain outputBlood loss volumeDegenerative disease of the lumbar spineRisk factorTransforaminal lumbar interbody fusion
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 837-842 )