Value Research of Plasma NT-proBNP,TyG Combined with CAAP-AF Score in Predicting Recurrence After Radiofrequency Ablation in AF Patients

XIONG Chen; CHEN Xiaodan; YAN Fengling

doi:10.13730/j.issn.2097-2148.2024.05.010

Abstract：Objective To analyze the clinical value of plasma nitrogenterminal B type natriureticpeptide precursor(NT-proBNP),triglyceride-glucose index(TyG)combined with coronary heart disease age atrial diameter paroxysmal at-rial fibrillation scoring system(CAAP-AF)in predicting recurrence after radiofrequency ablation in patients with atrial fi-brillation(AF).Methods A total of 226 patients with AF were divided into recurrent group(n=31)and non-recurrent group(n=195)according to whether AF recurred within 3 months after radiofrequency ablation.The clinical data such as age,sex,body mass index(BMI),cardiac function classification,basic diseases(coronary heart disease,hypertension,type 2 diabetes mellitus),smoking history and drinking history of AF patients between the two groups were compared,the expression levels of plasma NT-proBNP were detected,TyG was calculated,and the CAAP-AF scoring system was evaluated.The independent risk factors for the recurrence after radiofrequency ablation in AF patients were investigated by multivariate Logistic regression,and the clinical value of plasma NT-proBNP,TyG combined with CAAP-AF scores in predicting the recurrence after radiofrequency ablation in AF patients was analyzed by receiver operating characteristic(ROC)curve.Results The expression levels of plasma NT-proBNP,TyG and CAAP-AF scores of AF patients in the recurrence group were higher than those in the non-recurrent group,and the difference was statistically significant(all P＜0.01).The plasma NT-proBNP,TyG and CAAP-AF scores were independent risk factors for recurrence after radiofre-quency ablation in AF patients(P＜0.05).The area under the curve(AUC),sensitivity and specificity of plasma NT-proBNP,TyG combined with CAAP-AF in predicting the recurrence after radiofrequency ablation in AF patients were 0.829,90.32％and 81.03％respec-tively,which had high predictive value and were better than single indexes of plasma NT-proBNP,TyG and CAAP-AF(P＜0.05).Conclusion The detection of plasma NT-proBNP and TyG combined with CAAP-AF has a good clinical ap-plication value in the predicting recurrence after radiofrequency ablation in AF patients,which can be used as a clinical ref-erence predictor of recurrence after radiofrequency ablation in AF patients.