Effects of Simultaneous Transcranial Direct Current Stimulation Combined Transcutaneous Auricular Vagus Nerve Stimulation on Working Memory in Military Cadets
CHEN Chen
REN Lei
LIU Hongyao
LI Fengzhan
SONG Lei
ZHANG Liang
YANG Qun
Abstract：Objective To investigate the effects of simultaneous transcranial direct current stimulation(tDCS)combined transcutaneous auricular vagus nerve stimulation(taVNS)on the working memory of military cadets.Methods A two-factor mixed experimental design(group × number of measurements)was used to select 72 male un-dergraduate military cadets,who were randomly divided into 3 groups,the Sham group(receiving a sham stimulation in-tervention),the tDCS group(receiving a single tDCS stimulation)and the combined group(receiving simultaneous tDCS combined taVNS intervention),with 24 subjects in each.All 3 groups received the intervention twice a day for 3 consecu-tive days,with each interval of more than 4 h.The accuracy and reaction time of the letter 2-back paradigm were used to dynamically evaluate the changes of working memory ability of the subjects before and after the intervention,one week af-ter the intervention and one month after the intervention.Results The working memory ability of the tDCS group and the combined group was significantly improved after the intervention(P＜0.001),and the improvement effects of the com-bined group was better than that of the tDCS group.Conclusion Simultaneous tDCS combined taVNS intervention on working memory has certain feasibility and advantages,the same intervention time can achieve better effects and last lon-ger than single tDCS intervention.
Keywords：Transcranial direct current stimulationTranscutaneous auricular vagus nerve stimulationMulti-nerve fusion regulationPhysical regulationWorking memory
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1052-1056 )