Correlation Analysis Between Sleep and Diabetes Mellitus Under the Standardized Metabolic Management Model

LI Xia; BAI Xiaogang; MA Yue; LI Sheli; JIA Aihua

doi:10.13730/j.issn.2097-2148.2023.12.004

Abstract：Objective To describe the relationship between diabetes mellitus and sleep under standardized manage-ment,and to provide relevant evidences for blood glucose control in patients with type 2 diabetes mellitus(T2DM).Methods A total of 358 patients with T2DM treated and managed in the National Metabolic Management Center(MMC)branch center affiliated author's hospital from January 1,2020 to July 27,2021 were selected as the study subjects,the patients were divided into young group(≤40 years),middle-aged group(41-59 years)and elderly group(≥60 years)ac-cording to age.The gender,age and sleep status of the patients were collected,and the levels of fasting blood glucose(FBG),2-hour postprandial glucose(2hPG),glycosylated hemoglobin(HbA1c),C-peptide,triglyceride(TG)and total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C)were test-ed.The relationship between sleep status(nighttime sleep duration,sleep quality and siesta duration)and various indica-tors were analyzed.Results There were significant differences in the course of disease,SBP,body mass,120 min glu-cose,HbA1c,TG,HDL-C and LDL-C(P＜0.05);there was no difference in clinical indicators among patients with dif-ferent sleep quality and siesta duration(P＞0.05).Among patients with nighttime sleep duration＜6 h,there were sig-nificant differences in 0 min glucose,course of disease,TC and LDL-C among 3 groups(all P＜0.05).When nighttime sleep duration was 6-8 h,there were statistically significant differences in the course of disease and systolic blood pressure among the 3 groups(P＜0.01).There were statistically significant differences in the course of disease,body mass index(BMI),systolic blood pressure,HbA1c and LDL-C levels among the 3 groups of patients with nighttime sleep duration＞8 h(P＜0.05).Under the good sleep status,there were statistically significant differences in the course of disease,BMI,systolic blood pressure,HbA1c,TC and LDL-C levels among the 3 groups(P＜0.05);under the poor sleep status,there were statistically significant differences in the course of disease,systolic blood pressure and waist circ-umference among the 3 groups(P＜0.05).Conclusion There were no significant differences in clinical indicators among T2DM patients with different sleep duration,sleep quality and siesta duration,but there were significant differences in clinical indicators of different sleep duration and sleep quality among T2DM patients with different ages.