Clinical Research of Vacuum Sealing Drainage Combined with Fresh Frozen Plasma Perfusion in Diabetic Foot Ulcers
CHENG Lu
WANG Mei
ZHENG Jian-feng
LIU Qi
SONG Zhi-ren
Abstract：Objective To investigate the clinical effects of vacuum sealing drainage (VSD) combined with fresh frozen plasma (FFP) perfusion in treatment of diabetic foot ulcers.Methods Thirty-two patients with diabetic foot ulcer (Wagner classification:Ⅱ-Ⅳ) in author's hospital from August 20 1 4 to July 2016 were enrolled into this study.All patients all underwent surgical debridement.After the debridement operation,the patients were randomly divided into VSD group (n=16) and VSD combined with FFP perfusion (VSD+ FFP) group (n =16) by random number table.The thin intermediate thickness split skin grafting was given to cover the wound when the wound bed was preparated.The indexes including wound bed preparation time,would healing time,bacteria clearance rate after 10d and survival rate of skin grafts,were measured between two groups after treatment.Results Thirty-two patients with diabetic foot ulcers were all healed.The wound bed preparation time and would healing time in the VSD + FFP group were markedly shorter than those in the VSD group (P＜0.05).The bacteria clearance rate and survival rate of skin grafts in the VSD+ FFP group were remarkably higher than those in the VSD group (P＜0.05).Conclusion The combination of VSD+ FFP perfusion for treating diabetic foot ulcer has obvious advantages over the single VSD.VSD + FFP perfusion can shorten the wound bed preparation time,improve the bacteria clearance rate,increase the survival rate of skin grafts,and promote the wound healing.It is worthy of further study and clinical expansion.
Keywords：Diabetic footVacuum sealing drainageFresh frozen plasmaSkin graft
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 676-678 )