Qualities and Curative Effects of Single Donor Platelets and Buffy-coat-collected Platelets Concentrates
HE Yao-zong
GAO Yun-long
LIANG Zheng
ZHOU Hou-quan
LIU Si-jing
LU Yan-jun
WU Xin-zhong
Abstract：Objective To compare the qualities and curative effects of single-donor plateletapheresis (SDP) and buffy-coat-collected platelets concentrates (BC-PC),and provide a reference for rational use of two platelet concentrates.Methods A total of 100 packs of SDP and 100 packs of 400 ml BC-PC from whole blood in author's department from January 2015 to December 2016 were detected.The number of blood platelets,red blood cells (RBC) and white blood cells (WBC) were assayed and compared for qualities.Fifty-four patients transfused with SDP and fifty-two patients transfused with PC-PC were randomly selected in author's hospital.The corrected count increment (CCI) and percent platelet recovery (PPR) after 24-hour infusion were calculated,and rate of evaluation adverse transfusion reactions as well.Results There were no significant differences in the content of platelets between BC-PC (12U) and SDP (1U) (P＞0.05),but the white cell and erythrocytes assay in SDP were less than those in BC-PC (P＜0.05).No differences were found in CCI,PPR and rate of adverse transfusion reaction between two groups (P＞0.05).There were no differences in the curative effects of platelet infusion between hematopathic and nonhematopahic patients (P＞0.05).Conclusion BC-BC has certain effectiveness and safety.In order to alleviate the situation of platelet supply shortage,BC-PC can be used as powerful supplementary.
Keywords：Single-donor plateletsBuffy-coat-collected platelets concentratesQualitiesCurative effects
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 527-530 )