Imaging Features of 18F-FDG PET/CT in Autoimmune Pancreatitis

LI Guo-xiong; LIU Zhi-jun; YANG Xiu-rong; XIE Li-xuan; ZHANG Hai-jie; LI Zhong-quan; LIU Wei-wei

doi:10.13730/j.issn.1009-2595.2017.03.003

Abstract：Objective To investigate the imaging features of 18F-fluorodeoxyglucose (18F-FDG) positron-emission tomography/computed tomography (PET/CT) in autoimmune pancreatitis (AIP).Methods A total of 14 AIP patients' 18F-FDG PET/CT data in authors' hospital were retrospectively analyzed,the metabolic activity characteristics of the local pancreatic and extrapancreatic organs were analyzed,and average retention index (RI) of pancreatic lesions,early maximum standardized uptake value (SUVmax),delayed SUVmax were calculated and compared.Results Among 14 patients (5 males and 9 females),the average age was 49 years (ranged,31-67 years),11 patients with diffuse enlargement of pancreas,3 patients with local enlargement of the head of pancreas,the metabolic activity of the lesion site were increased.The main pancreatic duct in 10 patients showed diffuse stenosis,3 patients were localized and multifocal stenosis,1 patients was localized pancreatic duct stricture with proximal pancreatic obiliary dilatation,5 patients with peripancreatic sheath syndrome,3 patients with pancreatic leakage around.There were statistically significant difference in early SUVmax and the delayed SUVmax of 14 AIP patients(t=-6.63,P<0.05),and had no statistical difference between early SUVmax and delay SUVmax of 3 local pancreatic growth patients (t=-4.5,P=0.05).The difference among the early SUVmax,delayed SUVmax and RI were not statistically significant of patients with diffuse enlargement in pancreas (P>0.05).In 14 AIP patients,the changes of pancreatic external organs were found.The diagnostic accuracy of PET/CT was 71.40% (10/14),among which 3 patients was misdiagnosed as pancreatic head carcinoma,and 1 patient were misdiagnosed as acute pancreatitis.Conclusion 18F-FDG PET/CT AIP imaging has certain characteristics,and it is helpful to improve the correct rate and the accuracy of the disease.