Drug Resistance and Risk Factors Analysis of Acinetobacter Baumannii in Intracranial Infection Isolated in Patients with Craniotomy
REN Wei
LI Xiao-hong
CHU Mei-ling
WANG Lu
XUE Wen-cheng
YANG Jing
Abstract：Objective To analyze drug resistance and risk factors of Acinetobacter baumannii (Aba) in intracranial infection isolated from the patients with craniotomy,and provide the reference for clinical rational using of antibacterial agents and executing infection control measures.Methods The clinical data of 74 patients with intracranial infection in the authors' hospital during October 2012 to October 2015 were reviewed retrospectively.The pathogen distribution,resistance of Aba isolate and the risk factors caused intracranial infection were analyzed by SPSS 19.0 software.Results A total of 74 isolates were collected from the patients with craniotomy during 3 years.The most frequent pathogen isolated was Aba (58.1 ％).There was high drug resistance in Aba isolates.Multivariate logistic regression analysis showed pneumonia,tracheotomy,tracheal intubation,peripherally inserted central catheter (PICC) catheterization,nasal feeding were the independent risk factors of Aba intracranial infection after craniotomy (P＜0.05).Conclusion Resistant Aba is one most frequent pathogens in intracranial infection after craniotomy.Pneumonia,tracheotomy,tracheal intubation,PICC catheterization and nasal feeding are the independent risk factors of Aba intracranial infection.Relevant preventive measures should be strengthened to reduce the incidence of Aba intracranial infection.
Keywords：Intracranial infectionAcinetobacter baumanniiDrug resistanceRisk factors
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)