Observation of Curative Effect of Gastrin Receptor Antagonist on Metastatic Liver Tumors from the Large Intestine Carcinomas
Abstract：Objective To observe curative effect of the gastrin receptor antagonist on a metastatic liver concer in the patients with large intestine carcinomas. Methods Of the 84 patients in whom the large intestine carcinomas had metastasized to the livers, 46 in the therapeutic group were treated by both the conventional chemotherapy and the gastrin receptor antagonist, gastridine (1200 mg per day), and 38 in the control group only received the conventional chemotherapy. A follow-up per month was performed in the patients of both the groups. Results The diameter of the metastatic liver tumors increased by (3.5±1.2)cm and mortality was 21.9%(10/46) a year after the treatment in the therapeutic group, but the former increased by (8.1±2.2)cm, the latter was 55.3%(21/38) in the control group. Differences between the parameters of both the groups were statistically significant (P<0.01). Conclusions The metastatic liver tumors growth could be retarded, the survival time proloned and the mortality decreased by the treatment with the gastrin receptor antagonist in the patients with large inestine carcinomashaving metastasized to the livers.
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Publication Date：2001-04-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 9-10 )