Application of Roux-en-Y Gastric Bypass Surgery and Laparoscopic Sleeve Gastrectomy in Patients undergoing Weight Loss Surgery

Zhu Yanyan

doi:10.3969/j.issn.1004-5775.2026.01.016

Abstract：Objective:To observe the application effects of Roux-en-Y gastric bypass surgery(LRYGB)and laparoscopic sleeve gastrectomy(LSG)on patients undergoing weight loss surgery.Methods:As a prospective study,it selected 110 patients who underwent laparoscopic sleeve gastrectomy in the First People's Hospital of Nanyang from October 2021 to October 2023.The computer randomization method was used to generate a random sequence,and the enrolled patients were divided into the LRYGB group(55 cases)and the LSG group(55 cases).The postoperative follow-up was conducted for six months to compare the surgical situation,incidence of complications,digestive function,and weight loss effect of the two groups of patients.Results:Under different surgical plans,the LSG group had significantly lower surgical time,intraoperative blood loss,postoperative recovery of exhaust time,recovery of eating time,mobilization time,and hospitalization time compared to the LRYGB group,and the difference was statistically significant(P<0.05).The incidence of complications in the LSG group was lower than that in the LRYGB group,and the difference was statistically significant(P<0.05).Gastrin-17(GAS-17)in the LSG group was higher than that in the LRYGB group at 3 and 6 months of follow-up,and the pepsinogen Ⅰ/Ⅱ ratio(PGR)was higher than that of LRYGB group,and the difference was statistically significant(P<0.05).As of the end of follow-up,there was no statistically significant difference in BMI index,waist circumference,hip circumference,and percentage of excess weight loss(EWL)between the LSG group and the LRYGB group(P>0.05).Conclusion:The weight loss effects of LSG and LRYGB are comparable,but LSG could accelerate the postoperative recovery process of patients undergoing weight loss surgery,and has a positive significance in reducing the risk of surgical complications and alleviating digestive function damage.