Application of D-test in Drug Sensitivity Test of Group B Streptococcus
Lin Lichan
Shi Zongsheng
Xue Shicong
Abstract：Objective:Exploring the occurrence of erythromycin induced clindamycin resistance(D test)in group B streptococcus(GBS)to guide clinical doctors in rational drug use.Methods:BD bacterial identification instrument was used to detect the resistance of 39 strains of GBS isolated from Qingyuan Traditional Chinese Medicine Hospital to clindamycin and erythromycin;K-B paper method for detecting D test.Results:GBS had high sensitivity to penicillin,ampicillin,rifampicin,teicoplanin,amoxicillin/clavulanic acid,compound sulfamethoxazole,linezolid,and vancomycin;the resistance rate of GBS to clindamycin was 28.21%,and after the induced clindamycin test(ICT)correction,the resistance rate of GBS to clindamycin was 41.03%.Conclusion:The detection of clindamycin induction test should be carried out routinely to ensure the accuracy of clindamycin resistance detection,thereby improving the correctness of clinical antibiotic use.
Keywords：Group B streptococcusErythromycinClindamycinInducible clindamycin test
Publication Date：2025-10-10
Online Publishing Date：2025-11-05(First online date of this platform, not the publication date of the document)
Pages：4( 2359-2362 )