Observation on the Clinical Effect of Sodium Fondaparinum Injection for Anticoagulant Treatment in Patients with Threatened Miscarriage
Zang Rui
Abstract：Objective:To observe the clinical effect of Sudagan Sodium Injection on anticoagulant therapy in patients with threatened miscarriage.Methods:70 patients with threatened miscarriage who were treated in the hospital from October 2022 to October 2023 were divided into two groups using a random number table method,with 35 cases in each group.The control group was treated with low-molecular-weight heparin,while the observation group was treated with sulfamethoxazole sodium injection.The coagulation function,hormone levels,and adverse reactions between two groups were compared.Results:After treatment,the levels of fibrinogen(Fg)and D-dimer(D-D)in the observation group were lower than those in the control group,while the prothrombin time(PT),activated partial prothrombin time(APTT),and thrombin time(TT)were higher than those in the control group.The differences were statistically significant(t=4.904,3.159,3.346,3.662,4.659;P＜0.05).After treatment,the levels of estradiol(E2),progesterone(P),and β-human chorionic gonadotropin(β-hCG)in the observation group were all higher than those in the control group,and the differences were statistically significant(t=2.590,2.559,19.720;P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(χ2=4.200,P＜0.05).Conclusion:Anticoagulant treatment with sulfamethoxazole sodium injection in patients with threatened miscarriage can improve coagulation function;increase E2,P and β-hCG;and reduce the incidence of adverse reactions.
Keywords：Threatened miscarriageSuoda Gangui Sodium InjectionLow molecular weight heparinAnticoagulant therapyCoagulation function
Publication Date：2025-07-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1599-1601 )