Application Value of Susceptibility Weighted Imaging in Diagnosis of Brain Injury in Premature Infants

Tian Qidong; Sun Feng; Xie Chuanyong

doi:10.3969/j.issn.1004-5775.2025.07.023

Abstract：Objective:To explore the application value of susceptibility weighted imaging(SWI)in diagnosis of brain injury in premature infants.Methods:A retrospective study was conducted among 208 premature infants with brain injury(PIVH group)and 100 healthy premature infants(healthy control group)who were born during the period from January 2019 to March 2024.Imaging manifestations of conventional MRI sequences T1WI,T2WI and SWI were analyzed.Results:T1WI showed high signal or isointensity,T2WI showed low signal or high-low mixed signal,and SWI showed low signal.The detection rate of PIVH in SWI imaging was significantly higher than that in conventional MRI sequences,and the difference was statistically significant(x2=20.045,P＜0.001).SWI imaging showed that the lesion area of PIVH was significantly larger than that of conventional MRI sequences,with statistically significant difference(Z=10.384,P＜0.05).The detection rate of the number of lesions in PIVH lateral ventricle,choroid plexus,fourth ventricle and midbrain aquaquet by SWI imaging was higher than that in conventional MRI sequences,and the differences were statistically significant(x2=8.041,10.085,15.938,9.608;P＜0.05).The phase value of quantitative SWI imaging in PIVH group was higher than that in healthy control group,and the difference was statistically significant(Z=4.854,P＜0.05).The sensitivity and specificity of SWI imaging in the diagnosis of PIVH were 82.70％and 75.00％respectively.Conclusion:Compared with conventional MRI sequence,SWI can find microbleeds in diagnosis of premature infants with brain injury.Besides,it is more accurate in assessment of the number and size of lesions.Quantitative SWI can be used as a supplementary method.