Application of MSCT Perfusion Parameters Combined with Diffusion-weighted Imaging in Preoperative Evaluation of Gastric Cancer Patients

Zhang Huina

doi:10.3969/j.issn.1004-5775.2025.07.022

Abstract：Objective:To explore the application effect of multi slice spiral CT(MSCT)perfusion parameters combined with diffusion-weighted imaging in preoperative evaluation of gastric cancer patients.Methods:98 gastric cancer patients admitted to the Second Affiliated Hospital of Henan University of Science and Technology from September 2021 to September 2023 were selected,all of whom were scheduled for surgical treatment and underwent MSCT perfusion imaging and diffusion-weighted imaging before surgery.The postoperative pathological examination results were used as the gold standard to analyze the application value of MSCT perfusion parameters combined with diffusion-weighted imaging in preoperative evaluation of gastric cancer patients.Results:The blood flow,blood volume,and surface permeability values of patients in clinical stage Ⅲ were higher than those in stages Ⅰ～Ⅱ,and the apparent diffusion coefficient(ADC)value was lower than that in stages Ⅰ～Ⅱ,with statistically significant difference(t=4.440,4.153,3.472,4.302;P＜0.05).The surface permeability value of patients with low differentiation was higher than that of those with medium to high differentiation,while the ADC value was lower than that of those with medium to high differentiation,with statistically significant difference(t=4.986,5.517;P＜0.001).The area under the curve(AUC)values for evaluating preoperative clinical staging of gastric cancer patients using MSCT perfusion imaging parameters and diffusion-weighted imaging parameters alone and in combination were 0.773,0.739,0.722,0.754,and 0.915,respectively,all of which had certain evaluation value,and the combined evaluation value was the highest.AUC values of MSCT perfusion imaging parameters and diffusion-weighted imaging parameters for evaluating the preoperative differentiation degree of gastric cancer patients alone and in combination were 0.805,0.817,and 0.871,respectively,all of which had certain evaluation value,and the joint evaluation value was the highest.Conclusion:The combination of MSCT perfusion parameters and diffusion-weighted imaging has high evaluation value for preoperative clinical staging and differentiation degree of gastric cancer patients.