Retrospective Comparative Analysis of the Effect of Single Port and Traditional Multi Port VATS Pulmonary Nodule Resection on the Recovery Process and Prognosis of Patients with Solitary Pulmonary Nodules

Su Panlong; Miao Wang; Liu Fang

doi:10.3969/j.issn.1004-5775.2025.07.007

Abstract：Objective:To compare the effect of single port and traditional multi port video-assisted thoracoscopic surgery(VATS)for pulmonary nodule resection in the treatment of patients with solitary pulmonary nodules(SPN),and its impact on the recovery process and prognosis.Methods:The data of 100 patients with SPN in the hospital from January 2022 to March 2024 were collected,and they were divided into two groups according to the operation schemes.Among them,50 patients who received single port VATS pulmonary nodule resection were included in group A,and 50 patients who received traditional multi port VATS pulmonary nodule resection were included in group B.The levels of operation and postoperative recovery indicators were compared between the two groups,as well as the levels of lung function[diffusing capacity of the lungs for carbon monoxide(DLCO),forced vital capacity(FVC),maximum ventilation volume(MVV)]before and 1 month after operation,visual analogue scale(VAS)scores at 1 d,3 d,7 d after operation,stress injury indicators[malondialdehyde(MDA),substance P(SP),superoxide dismutase(SOD),C-reactive protein(CRP)]before and 3 d after operation,and the incidence of complications was compared between the two groups.Results:The first time getting out of bed and hospitalization time in group B were longer than those in group A,and the intraoperative blood loss and postoperative drainage volume in group B were lower than those in group A,with statistically significant difference(t=9.051,13.153,10.712,18.479;P＜0.05).1 month after surgery,the levels of DLCO,FVC and MVV in group A were higher than those in group B,with statistically significant difference(t=7.768,6.881,7.500;P＜0.05).The VAS score of group A was lower than that of group B 1 d 3 d and 7 d after surgery,and the differences were statistically significant(t=7.832,8.318,13.373;P＜0.05).3 days after surgery,the levels of MDA,SP and CRP in serum of group A were lower than those of group B,and the levels of SOD were higher than those of group B,with statistically significant difference(t=7.285,24.832,5.897,9.123;P＜0.05).The complication rate of group B was higher than that of group A,and the difference was statistically significant(x2=5.005,P＜0.05).Conclusion:Compared with the multi hole VATS pulmonary nodule resection in the treatment of SPN patients,the single hole VATS pulmonary nodule resection can reduce the complications,the stress injury to the body is more mild,and the impact on lung function is less.Resection treatment is more helpful to reduce intraoperative blood loss and postoperative drainage,shorten the recovery process,and reduce postoperative pain.