Evaluation of the Effect of Danzhi Binghe Compound Traditional Chinese Medicine Monomer Capsule on Restenosis After PCI by IVUS

Zeng Ziwei; Zhou Zhuhua; Xu Tao

doi:10.3969/j.issn.1004-5775.2025.07.003

Abstract：Objective:To evaluate the effect of Danzhi Bingmusia compound capsule on restenosis after coronary intervention(PCI)by intravascular ultrasonography(IVUS).Methods:A total of 80 patients with cardiovascular diseases admitted to sample hospitals from February 2019 to October 2022 were selected as research objects,and they were divided into control group and observation group according to random number table method,with 40 cases in each group.Two groups in the perioperative period received conventional drug treatment,and observation group received Danzhi ice musk deer compound monomer capsule on the basis of control group.The efficacy,restenosis degree,improvement of blood stasis symptom and occurrence of adverse reactions were compared between the two groups.Results:After PCI,the main symptoms of angina pectoris,such as chest pain and chest tightness,disappeared in both groups,and ST-T indicated significant improvement or normal.The recurrence rate of angina pectoris in the observation group was lower than that in the control group,with statistically significant difference(x2=9.038,P＜0.05).6 months after operation,the total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(x2=5.165,P＜0.05).6 months after operation,the restenosis rate of observation group was lower than that of control group,and the difference was statistically significant(x2=3.914,P＜0.05).IVUS results showed that the minimum lumen area of the left main trunk in the observation group was smaller than that in the control group,and the difference was statistically significant(t=28.479,P＜0.05).The improvement of blood stasis symptoms in observation group was better than that in control group,and the difference was statistically significant(x2=6.667,P＜0.05).Conclusion:The IVUS results show that Danzhi and musk deer compound monomeric capsule is safe and effective in patients after PCI.