Analysis of Serum Anti-nuclear Antibody Assay Results of 1 047 Cases in Fengtai District,Beijing

Sun Mengyang; Li Min; Jing Shuxian

doi:10.3969/j.issn.1004-5775.2025.06.016

Abstract：Objective:To retrospectively analyze the results of anti-nuclear antibody spectroscopy of 1 047 patients in Fengtai District,Beijing.Methods:A total of 1 047 patients treated in Beijing Aerospace General Hospital from September to November 2023 were selected as the study objects.ANAs was detected by western blotting,and the test results were analyzed.Results:Among 1 047 patients,172 were ANAs positive,with a total positive rate of 16.43%.The top 5 antibody positive rates were anti-RO-52 antibody,anti-U1-NRNP antibody,anti-SS-A antibody,anti-histone antibody and anti-SM antibody.According to gender classification,there were 497 male samples,of which 68 were positive specimens,with a positive rate of 13.68%,and 550 female samples,of which 104 were positive specimens,with a positive rate of 18.91%.The positive rate of female samples was higher than that of male samples,the difference was statistically significant(χ2=5.195,P＜0.05).According to age classification,there were 30 positive samples in the age group less than 40 years old,the positive rate was 2.87%.There were 46 positive samples in 41 to 60 age group,the positive rate was 4.39%.There were 96 positive samples in the age group over 60 years old,and the positive rate was 9.17%.Conclusion:The positive rate of female specimens is higher than that of males.With the increase of age,the positive rate increases gradually.