Application of Thoracic Paravertebral Nerve Block Assisted General Anesthesia in Radical Surgery for Lung Cancer

Zhang Zhen

doi:10.3969/j.issn.1004-5775.2025.05.003

Abstract：Objective:To observe the application effect of TPVB assisted general anesthesia in radical lung cancer surgery.Methods:The subjects of this study were 100 patients with radical resection of lung cancer admitted to Zhengzhou Central Hospital Affiliated to Zhengzhou University from October 2022 to November 2023.The study method was a prospective study,and the patients were divided into the routine group(50 cases)and the combined group(50 cases)by computer randomization.The conventional group was treated with general anesthesia,and the combined group was treated with TPVB combined with general anesthesia.The perioperative basic signs,postoperative analgesia,sedation,anesthesia recovery,surgical stress reaction and anesthesia safety were compared between the two groups.Results:When peeling,HR and MAP in combination group were lower than those in conventional group,with statistically significant difference(t=2.398,3.699;P＜0.05).1 h and 3 h after operation,VAS score and RSS score of combination group were lower than those of conventional group,and the differences were statistically significant(t=2.294,4.714,7.085,15.807;P＜0.05).The eye opening time,PACU stay time,time transferred to the general ward and hospital stay in the combined group were higher than those in the conventional group,with no statistically significant difference(t=0.717,0.992,1.152,0.596;P＞0.05).After surgery,both groups had some surgical stress reactions,but the NE and Cor of the combined group were lower than those of the conventional group,the differences were statistically significant(t=3.655,3.726;P＜0.05).The incidence of anesthesia-related side effects in combination group was higher than that in conventional group,and the difference was not statistically significant(x2=0.889,P＞0.05).Conclusion:TPVB assisted general anesthesia can effectively stabilize the perioperative basic signs of patients undergoing radical resection of lung cancer,enhance postoperative analgesia and sedation,and relieve surgical stress without affecting anesthesia recovery.And it has high safety.