Evaluation of Serum Cystatin C and Homocysteine Levels in Patients with Hemiplegic Patient After Acute Cerebral Infarction
Wu Daoqiu
Chen Haijun
Luo Ling
Abstract：Objective:To explore the expression levels of serum cystatin C(Cys C),homocysteine(Hcy)and low-density lipoprotein(LDL)of hemiplegic patients after acute cerebral infarction(ACI),and analyze their prognostic value of ACI hemiplegic patients.Methods:A total of 100 patients with ACI hemiplegia admitted to Leizhou People's Hospital from April 2021 to May 2023,and 50 normal medical examiners who underwent health checkups were selected as the study subjects.Patients with ACI hemiplegia were in the observation group,and normal medical examiners were in the control group.General clinical data,the serum levels of Cys C,Hcy and LDL of the two groups were compared.The predictive value of this method for the prognosis of ACI patients was determined by logistic regression analysis and ROC curve.Results:The levels of serum Cys C,Hcy and LDL were significantly higher in observation group than in control group(t=8.88,22.69,4.346;P＜0.05).According to logistic regression analysis,Serum Cys C,Hcy and LDL levels were risk factors for poor prognosis in patients with ACI hemiplegia.ROC curve analysis showed that the combination of CysC,Hcy and LDL levels had the highest value in predicting adverse prognosis in ACI patients,and the optimal cut-off value was 1.21 mg/L,21.52 μmol/L and 3.13 mmol/L.Conclusion:Serum Cys C,Hcy and LDL levels are correlated with the prognosis of patients with ACI hemiplegia,and the two combined tests are of great value in evaluating the prognosis of patients.
Keywords：Cystatin CHomocysteineLow-density lipoproteinAcute cerebral infarctionHemiplegicPrognosis
Publication Date：2025-02-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 325-327 )