Clinical Application of PRF in GBR of Maxillary Anterior Teeth
Wang Jianbo
Liu Tingting
Zhang Na
Abstract：Objective:To observe the clinical effect of platelet rich fibrin(PRF)combined with Bio-oss bone powder as bone filling material on bone remodeling in the maxillary anterior region during GBR guided bone regeneration surgery.Methods:40 implant patients who require GBR bone regeneration surgery in the maxillary anterior teeth area were selected as the study subjects.They were divided into two groups based on different surgical procedures,with 20 patients in each group.During the GBR procedure in the experimental group,PRF combined with Bio-oss bone powder was used as bone filling material and implanted with implants simultaneously,while in the control group,artificial bone powder was simply implanted with implants simultaneously.On the same day,3 months,6 months,and 12 months after surgery,imaging examinations were conducted to observe and record the changes in bone density and labial ossification thickness of the maxillary anterior teeth in two groups for each cycle,as well as the stability of the implant and the occurrence of complications.Results:A total of 45 implants were implanted in 40 patients,with good wound healing around the implants,no infection,and no failure or detachment of the implants.There was significant difference in bone density between the two groups in the maxillary anterior region(F=1 1.300,P＜0.05).The stability of the experimental group's implants was better than that of the control group.The incidence of complications was lower than that of the control group(F=1.070,1.120;P＜0.05).Measurement of the osteogenic thickness on the labial side of two groups of maxillary anterior teeth revealed little difference between the two groups,and statistical analysis showed no significant difference between the two groups(P＞0.05).Conclusion:PRF combined with Bio-oss bone powder as bone filling material can improve the remodeling of bone tissue in the maxillary anterior teeth area,accelerate the metabolism of bone filling material,promote new bone formation,and improve implant stability.It also reduces the occurrence of complications and has good clinical value.
Keywords：Rich platelet fibrinGuided bone regeneration surgeryPlantation
Publication Date：2025-02-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 300-302,305 )