Discussion on the Value of Fibrinogen and High-density Lipoprotein Combined Test to Predict Deep Vein Thrombosis After Traumatic Lower Limb Fracture
Yan Hongliang
Dong Sen
Wang Yanqing
Abstract：Objective:To investigate the predictive value of fibrinogen(Fib)and high-density lipoprotein(HDL)for deep vein thrombosis(DVT)after traumatic lower limb fracture.Methods:Selecting 75 postoperative patients of traumatic lower extremity fracture in Trauma Orthopedic Department from December 2020 to December 2022 and dividing them into DVT group(n=29)and non-DVT group(n=46).Serum Fib and HDL,and the predictive value of serum Fib and HDL on postoperative DVT of traumatic lower extremity fracture were analyzed.Results:The Fib level in the DVT group was higher than that in the non-DVT group,and the serum HDL level was lower than that in the non-DVT group,with statistically significant difference(t=14.857,6.613;P＜0.05).The area under the combined ROC curve(AUG)of serum Fib and HDL was higher than that of single detection.Conclusion:The serum Fib and HDL levels are closely related to the occurrence of postoperative DVT after traumatic lower extremity fracture,and the combined detection of both patients is of great significance for the early diagnosis and treatment of postoperative DVT after traumatic lower extremity fracture.
Keywords：Traumatic lower extremity fractureDeep vein thrombosisFibrinogenHigh density lipoproteinPredictive value
Publication Date：2024-11-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2716-2718 )