Analysis of the Correlation between Neonatal Birth Weight and Neonatal Hyperbilirubinemia
Li Haifeng
Pan Sinian
Liang Yayong
Abstract：Objective:To investigate whether there is a correlation between neonatal birth weight and neonatal hyperbilirubinemia(NHB).Methods:Information about all children admitted to the neonatal intensive care unit(NICU)was extracted from the Medical Information on Intensive Care database(MIMIC-III),and after excluding children who were not first-time admissions to the NICU,who were not newborns,and who had no information about their birth weights,4 882 newborns were finally included in the study.The children were equally divided into five groups according to their birth weight.The independent correlation between birth weight and NHB was assessed using a multifactorial logistic regression generalized summation model.Results:A total of 4 882 newborns were included in the analysis.There was a nonlinear correlation between birth weight and NHB by logistic regression modeling and smoothing curves.When the birth weight of the children was between 1.55 kg and 3.52 kg,the effect value was 0.246,and the difference was statistically significant(OR=0.246;CI=0.193-0.314,P＜0.001).There was no statistically significant difference in the relationship between weight and disease when weight was less than 1.55 kg or when weight was greater than 3.52 kg(P＞0.05).Conclusion:There was a nonlinear relationship between neonatal birth weight and NHB,with a 75.4%reduction in the risk of NHB for each 1 kg increase in birth weight between 1.55 kg and 3.52 kg.
Keywords：Birth weightNeonatal hyperbilirubinemiaIntensive care medical information databaseNeonatal intensive care unit
Publication Date：2023-12-31
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2965-2968 )