Analysis of Clinical Pharmacist Involvement in the Treatment of Abnormal Coagulation Caused by Cefoperazone Sulbactam Sodium
Zhang Miao
Zhong Han
Abstract：Objective:To analyze the treatment process of a case of cefoperazone sulbactam causing coagulation abnormalities in a patient and to discuss the role of clinical pharmacists in the safe use of medication in patients.Methods:Clinical pharmacists analyzed the causes of coagulation abnormalities in patients,make pharmacological recommendations for the patients'treatment process,and carry out pharmacological monitoring and pharmacological follow-up after patients were discharged from the hospital.Results:The clinical pharmacist,taking into account the patients'condition and reviewing the literature,analyzed that the adverse drug reaction was caused by cefoperazone sulbactam sodium and recommended switching to piperacillin tazobactam,which has less effect on the patients'coagulation function,as well as giving Bifidobacterium bifidum live adjuvant therapy.The patients'coagula-tion function gradually returned to normal.Conclusion:Clinical pharmacists ensure the safe and rational use of medication by par-ticipating in the patients'treatment process and carrying out pharmacological monitoring.
Keywords：Cefoperazone sodium and sulbactam sodiumCoagulation abnormalitiesPharmacistsPharmaceutical care
Publication Date：2023-12-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2864-2866 )