Clinical Observation of Compound Matrine Injection Combined with TP Chemotherapy in the Treatment of Non Small Cell Lung Cancer

doi:10.3969/j.issn.1004-5775.2019.01.27

Abstract：Objective To investigate the clinical efficacy of compound matrine injection combined with paclitaxel + cisplatin (TP) chemotherapy in the treatment of non-small cell lung cancer.Methods A total of 154 patients with non-small cell lung cancer inthe hospital from September, 2017 to March, 2018 were selected as the subjects.According to the number in accordance with the or-der of admission, they were randomly divided into the observation group and the control group, with 77 cases in each group.The con-trol group were treated with TP regimen, and the observation group were treated with compound matrine injection combined with TPregimen. The clinical efficacy, quality of life and side effects of the two groups were observed.Results The effective rate of the observa-tion group was higher than in the control group. The difference was statistically significant (P＜0.05). The improvement of the qualityof life of patients in the observation group was better than the control group. The difference was statistically significant (P＜0.05). Allkinds of adverse reactionsin the observation group was significantly better than the control group. The difference was statistically signifi-cant (P＜0.05).Conclusion Compound matrine injection combined with TP chemotherapy is effective in the treatment of non-small cell lung cancer. It can effectively reduce the incidence of side effects, so it is worthy of application and promotion.