Efficacy of Irbesartan Combined with Amlodipine on Elderly Patients with Hypertension and Type 2 Diabetes

PENG An-yang; SHEN Wan-gui; HU Xing-li

doi:10.3969/j.issn.1004-5775.2016.11.024

Abstract：Objective To evaluate the clinical efficacy of irbesartan combined with amlodipine in treatment of elderly hypertensive pa -tients with type 2 diabetes.Methods A total of 92 elderly patients with type 2 diabetes who were diagnosed with hypertension in the hospital from January, 2012 to January, 2016 were selected.There were 31 cases in control group A , and they separately used amlodipine maleate . There were 31 cases in control group B , and they separately used irbesartan .There were 30 patients in the observation group , and they used irbesartan and ammonia chlorine horizon.After 10 weeks, the total effective rate, blood pressure, blood lipid level and incidence of side effects were compared among three groups after 1 courses of treatment.Results After treatment, the total efficiency in observation group is higher than that of the control group A and B (P<0.05).In the observation group, lower blood pressure (systolic blood pressure and dias-tolic blood pressure ) is better than that of the control group A and B ( P<0.01 ) .Fall blood fats curative effect in observation group is obviously superior to the control group A and B (P<0.01).In the treatment process, vice reaction rate is low.Conclusion Clinical cur-ative effect of irbesartan combined with amlodipine in the treatment of elderly hypertensive patients with type 2 diabetes is good , with low danger coefficient .So it is worthy of clinical application .