Observation on the Effect of Astragalus Membranaceus Combined with Ligustrazine in Fumigation-washing Therapy for Diabetic Peripheral Neuropathy (DPN)
Abstract：Objective To evaluate the effect of Astragalus membranaceus combined with ligustrazine in fumigation -washing therapy for diabetic peripheral neuropathy ( DPN) and its influence on nerve conduction velocity.Methods A total of 120 patients with DPN were randomly assigned to the group receiving combined treatment of traditional Chinese and western medicine , the group receiving treatment with Western medicine , and the control group.After a 4-week treatment ( treatment with ligustrazine lasted only 2 weeks ) , the clinical effects and the changes of nerve conduction velocity before and after the treatment in the three groups were evaluated .Results There were signifi-cant differences in Toronto CSS Scores and nerve conduction velocity before and after the treatment in each group ( P<0.05 ).In compari-son with the western medicine group and the control group , Toronto CSS Scores and nerve conduction velocity in the group receiving com -bined treatment of traditional Chinese and western medicine were significantly altered after the treatment ( P<0.05 ).Compared with the control group , the indicators mentioned above were also significantly changed in the western medicine group after the treatment ( P<0.05 ).Conclusion Fumigation-washing therapy with Astragalus membranaceus combined with ligustrazine is able to increase nerve conduction velocity significantly and effectively improve the symptoms and signs of patients with DPN.It is suggested that this therapeutic method may effectively control and postpone the development of DPN , and it is worth to be extensively learned and applied in clinic.
Keywords：Astragalus membranaceusDiabetic peripheral neuropathy ( DPN)Effect observation
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1009-1011 )