Clinical Observation of Lappaconite for Postoperative Analgesia in Patients Undergoing Thyroid Surgery
GAO Li-li
KANG Shuang
Abstract：Objective To compare the efficacy of different doses of lappaconite hydrobromide for postoperative analgesia in patients un-dergoing thyroid surgery.Methods 60 patients under thyroid surgery were divided into three groups:lappaconite hydrobromide 0.15 mg/kg (group L1), 0.20 mg/kg (group L2) diluted to 20ml before operation, and the control group(group C).Pain intensity was measured using VAS scores at the 2, 4, 6, 8, 12 and 24 hours after operation.The adverse reaction and the number of patients asking for analgesics were recorded.Results Demographic data including sex, age, body weight and operation time were similar among the three groups.There were significant differences of VAS scores in group L1 and group L2 at 2~24 h compared with group C.VAS scores in group L2 were lower than group L1 at 2 h and 6 h, with stastical difference( P<0.05).Conclusion Lappaconitine for patients with postoperative analgesic effect do thyroid surgery all safe and reliable, and in the latter early stage, patients have stronger analgesic effect.
Keywords：LappaconitineThyroidAnalgesiaPostoperation
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 771-772,773 )