Influence of Subclinical Hypothyroidism on the Levels of Serum Lipid, C-reactive Protein and Cardiac Function for Elderly Dia-betic Patients
CHENG Wei
XIAO Hui-sheng
Abstract：Objective To study the influence of subclinical hypothyroidism (SCH) on the levels of serum lipid, C-reactive protein and cardiac function for elderly diabetic patients .Methods Elderly diabetic patients with combined SCH and without SCH were regarded as the subjects of the observation group and the control group , with 240 patients in each group .The levels of serum thyroid stimulating hor-mone ( TSH) , triglyceride ( TG) , total cholesterol ( TC) , C-reaction protein ( CRP) , brain natriureic peptide ( BNP) , left ventricular e-jection fraction ( LVEF) in the two groups were observed and compared .Results Through comparing with the control group , the levels of TSH(6.5 ±2.1 vs 1.8 ±1.0)mU/L,TG(1.8 ±0.5 vs 1.4 ±0.4)mmol/L, TC (5.8 ±0.7 vs 4.4 ±0.4)mmol/L were significantly in-creased in the observation group (P<0.05);through comparing with the control group , the levels of CRP(4.8 ±1.4 vs 3.1 ±1.3)mg/L, BNP (94.2 ±11.3 vs 72.1 ±10.7)pg/mL were obviously increased and the level of LVEF (56.4 ±8.5 vs 61.5 ±9.0)%was significantly reduced in the observation group (P<0.05).Conclusion The subclinical hypothyroidism can lead to the abnormal lipid metabolism , ele-vate the level of CRP , and reduce the left ventricular systolic function .
Keywords：Subclinical hypothyroidismDiabetesBlood fatCRPHeart functionSenile patient
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 648-649 )