Analysis of Antibiotic Use Intensity and Pharmacoeconomics in Respiratory Medicine
HUANG Wei-qiang
DENG Yao-guang
LUO Rui-xun
Abstract：Objective To evaluate the antibiotic use intensity and pharmacoeconomics in respiratory medicine in the hospital and to provide a guideline for rational antibiotics use .Methods Totally 328 patients who discharged from the respiratory medicine department from June, 2012 to June, 2014 were enrolled in the study.Defined daily doses (DDDs), antibiotic use density (AUD) and drug utilization index ( DUI) were recorded.The correlation between AUD and bacterial resistance was evaluated by linear regression analysis .DDDs and DUI were evaluated by pharmacoeconomics .Results The daily AUD was 108.6 DDD per 100 persons.The correlation coefficient of the top 10 DDDs and bacterial resistance was r=0.657, P<0.05.The cephalosporin was relatively high in daily cost , DUI<1.However, levo-floxacin, amoxicillin, piperacillin/sulbactam were relatively low in daily cost ,DUI>1.Conclusion AUD is over the use strength in the Department of Respiratory Medicine in the hospital , so it should be applied rationally , and be divided scientifically and designedly according to“Antibiotics Clinical Application Guidance Principle”.Based on this, cheap and effective antibiotics can remit the cost burden of patients.
Keywords：Respiratory MedicineAntibioticsPharmacoeconomicsAUDBacterial Resistance
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 639-640,641 )