Thrombus Aspiration Combined with Tirofiban in Clinical Observation of ST Segment Elevation AMI Emergency in the Treat-ment of PCI
JI Wei-qing
ZHANG Hui-qi
Abstract：Objective To observe the effect of thrombus aspiration combined with tirofiban in ST segment elevation myocardial infarc -tion (ST segment elevation myocardial infarction , STEMI) in emergency percutaneous coronary interventional therapy (Percutaneous coro-naryinterventions,PCI)therapy.Methods 40casesacuteSTEMIpatientswereselectedinthehospital.Accordingtothedifferenttreat-ment methods of patients , they were divided into two groups , with 20 cases in each group.A group had thrombus aspiration +tirofiban combined with intravenous administration , and B group had thrombus aspiration .The percentage of ST elevation down , peak plasma cardiac troponin I (cTnI), left ventricular end diastolic diameter (LVDd), left ventricular ejection fraction (LVEF), bleeding and major adverse cardiac event rate etc of the two groups were observed .Results ST segment elevation drop percentage , cTnI value , LVDd and LVEF in A group were significantly better than those in B group , and there was significant difference (P<0.05).There were no significant difference between major bleeding and major adverse cardiac event rate and so on of the two groups (P>0.05).Conclusion Thrombus aspiration +tirofiban intravenous combined coronary artery administration application and STEMI emergency PCI can effectively reduce the incidence of no reflow and improve myocardial perfusion and prognosis , so it is worthy of promotion.
Keywords：ST segment elevation myocardial infarctionThrombus aspirationTirofibanPercutaneous coronary interventionCurative effect
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 626-628 )