Effect of Thalassemia Carrier on the Chemotherapy Induced Anemia in Patients with non-Hoking Lymphoma and Protection Role of Yisuishengxue Granule
Abstract：Objective To observe the effect of thalassemia carrier on the chemotherapy induced anemia in patients with non -Hodking lymphoma(NHL)andprotectionroleofYisuishengxuegranule.Methods 38patientswithNHLcomplicatedwiththalssemiawerestudied. 38 patients with NHL not complicated with thalssemia were selected .Hemoglobin levels among the first course of CHOP chemotherapy were detected .Those patients with thalassemia were further classified into groups in the second course of chemotherapy : for treatement group , Yisuishengxue granules were used together with chemotherapy ,and for observe group ,merely chemotherapy was adapted .Also hemoglobin levels were detected during chemotherapy .Results Through comparing with patients without thalssemia ,hemoglobin decreased level was significantly higher in patients with thalssemia (8.6 ±5.2)g/L vs (5.8 ±4.4)g/L,with significant statistical significance (P=0.013). During the second course of chemotherapy in patients with NHL complicated with thalassemia ,decreased hemoglobin level in patients treated with Yisuishengxue granule was significantly lower than those patients not treated with Yisuishengxue granule (2.2 ±2.3)g/L vs( 4.5 ± 4.1 ) g/L,with significant statistical meaning , P=0.0398.Conclusion Patients′concurrent NHL and thalassemia is common in Southern China.Concurrent thalassemia aggravates chemotherapy induced anemia in patients with NHL .Yisuishenxue granule may alleviate chemo-therapy induced anemia in patients with NHL complicated with thalassemia .
Keywords：Non-Hodking lymphomaThalssemiaChemotherapy induced anemiaYisuishengxue granule
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 610-611 )