Clinical Effects Evaluation of 24 Weeks Entecavir Antiviral Therapy on Chronic Hepatitis B
XIAO Chun-hua
CHEN Wei-lie
WEI Shao-jing
Abstract：Objective To study the clinical effects of 24 weeks entecavir antiviral therapy on chronic hepatitis B.Methods A total of 140 patients, received from April 2013 to April 2014, with chronic hepatitis B were included in this study and randomly divided into study group and control group.Patients in control group were treated by adefovir dipivoxil and patients in study group were treated by entecavir ad-ditionally.The clinical effects were compared between two groups.Results The HBV DNA load in study group was significantly lower than that in control group, at 6 weeks, 12 weeks and 24 weeks after treatment.There was no significant difference of serum TGF-β1 between two groups(P>0.05).Conclusion Entecavir is a effective adjuvant drug in chronic hepatitis B antiviral therapy.
Keywords：EntecavirHepatitis BAntivirus
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 520-521,522 )