Analysis the Risk Factor of Bilirubin Encephalopathy of Neonatal Hyperbilirubinemia
Abstract：Objective Analysis the risk factor of bilirubin encephalopathy of Neonatal .And provides the measurement to decrease hy-perbilirubinemia bilirubin encephalopathy incidence.Methods Retrospective analysis 209 neonatal hyperbilirubinemia patients′clinical data.Definite bind the score 7-9 points as acute bilirubin encephalopathy (ABE).the children ABE as the observation group (n=40 pa-tients), the rest patients as the control group (n=169 patients).Related factors that may affect the incidence of hyperbilirubinemia ABE were univariate and multivariate Logistic regression analysis, the Related factors include gender, neonatal gestational age, birth weight, mode of delivery, fetal membranes early break, feeding patterns, gestational diabetes, gestational hypertension, asphyxia or fetal distress,the peak total bilirubin, jaundice family history, RH hemolytic disease and ABO hemolytic disease.Results It was found that birth weight (OR=3.739,95%CI:1.240 -11.880), total bilirubin peak (OR=6.475,95%CI:1.724 -17.419), RH hemolytic disease(OR=11.473,95%CI:2.708-33.697)and ABO hemolytic disease (OR=9.143,95%CI:2.492-28.513)were the risk factors for neonatal hy-perbilirubinemia bilirubin encephalopathy after multivariate Logistic regression analysis, P<0.05.Conclusion Birth weight, total biliru-bin peak, RH hemolytic disease and ABO hemolytic disease are related to bilirubin encephalopathy, clinicians should strengthen Screening and treat the very low birth weight, high total bilirubin peak, accompanied by RH hemolytic disease and ABO hemolytic patients.
Keywords：NewbornsHyperbilirubinemiaBilirubin encephalopathyRisk Factors
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 506-508 )