Clinical Study of Electrophonophoresis with Shenbai Patch via Acupoint in the Prevention of Chemotherapy-induced Marrow Depression
XU Shu
REN Xian-song
LONG De
Abstract：Objective To evaluate the preventive effect of electrophonophoresis with Shenbai Patch via acupoint on chemotherapy-in-duced marrow depression.Methods Total ninety tumor patients given ordinal chemotherapy were randomized into group A, group B and group C equally.Sufferers in group A and B were administered electrophonophoresis via Foot Three Li or Xuehai acupoint five days before chemotherapy.The whole treatment was seven days and Group A was additionally given ShenBai Patch.Marrow depression and gastrointesti-nal reactions induced by chemotherapy were recorded later.Results There were significant differences in the total marrow depression rate among the three groups (P=0.035).Group A had the lowest counts with only 40.0% compared with Group B (66.7%) and Group C (70.0) .Both Group A and Group B showed less gastrointestinal reactions such as severe nausea ( Group A with 10.0% incidence VS Group B 13.3% VS Group C 33.3%, P=0.044 ) and vomiting ( Group A with 26.7% incidence VS Group B 30.0% VS Group C 56.7%, P=0.032).Furthermore, no skin rash or allergy was observed in Group A or Group B.Conclusion Electrophonophoresis with Shenbai Patch via acupoint can effectively prevent marrow depression induced by chemotherapy.Patients who would suffer mild marrow sup-pression may benefit more from the therapy.In addition, simple electrophonophoresis via acupoint may ease gastrointestinal reactions in chemotherapy to some extent.The therapeutic schedule is safe and efficacious.
Keywords：ElectrophonophoresisAcupointChemotherapyShenbai PatchMarrow depressionGastrointestinal reactions
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 502-504 )