The Changes and Clinical Significance of Arterial Blood Gas Index in Children Severe Asthmatic Diseases Combined Pulmonary Hypertension

LIN Guo-dong; LI Chun-hua; HUANG Hai-zhong

doi:10.3969/j.issn.1004-5775.2015.05.013

Abstract：Objective To study the changes and its clinical significance of arterial blood gas index in children severe asthmatic disea-sescombinedpulmonaryhypertension.Methods 82casesofsevereasthmaticdiseasepatientswereselectedfromadmittedinpatientduring January 2011 to September 2014, according to whether combined pulmonary hypertension patients can be divided into pulmonary hyperten-sion group (35 cases) and none-pulmonary hypertension group (47 cases), arterial blood gas index PaO2, PaCO2 and SaO2 between groups were evaluated, and blood gas index in different periods of children severe asthmatic diseases combined pulmonary hypertension were statistically analyzed.Results The blood gas analysis showed, PaO2 , SaO2 of pulmonary hypertension group were obviously lower than none-pulmonary hypertension group, but PaCO2 was significantly higher than none-pulmonary hypertension group (P<0.05).Compared with remission, PaO2 , SaO2 of pulmonary hypertension group acute exacerbation showed a trend of rise, and PaCO2 was markedly reduced (P<0.05).ROC curve analysis showed, the area under the ROC curve (AUC)in PaO2, PaCO2, SaO2 combined detection for forecast se-vere asthmatic diseases combined pulmonary hypertension illness was 0.914, significantly higher than PaO2(0.812), PaCO2(0.804) and SaO2(0.754) (P<0.05).Conclusion The arterial blood gas index PaO2, SaO2 value of children severe acute asthmatic disease with pulmonary hypertension in are decreased, PaCO2 value increases, all changes by illness, and used as prognosis evaluation referent index for severe acute asthmatic disease combined pulmonary hypertension .