Effect of Gemcitabine and Cisplatin in the Treatment of Advanced Triple-negative Breast Cancer
LüYe
LIN Feng
MAO Wei-dong
Abstract：Objective To observe the effect of Gemcitabine and Cisplatin in the treatment of advanced triple -negative breast cancer.Methods 30 patients with advanced triple -negative breast cancer were treated by Gemcitabine and Cisplatin.The effects were observed after at least 2 weeks′therapy.Results All 30 patients were available for objective response , CR 2 cases(6.7%), PR 8 cases(26.6%), SD 11 cases(36.7%), PD 9 cases(30.0%), and the overall response rate (CR+PR) was 33.3%.After 1 year′s follow-up, the medi-an survival duration was 5.4 months; the main treatment -related toxicities were bone marrow depression and gastrointestinal reaction.Grade Ⅲ~Ⅳtoxicity mainly included neutropenia and thrombocytopenia , and there was no related death disease.Conclusion Gemcit-abine combined with cisplatin is effective in the treatment of patients with advanced breast cancer with acceptable toxic reaction .It may be an effective regimen.
Keywords：Breast cancerGemcitabineCisplatin
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1352-1353 )