Influence of the Hemorheology, LPO and SOD Level of Simvastatin with Breviscapine on Patients with Coronary Heart Disease
LUO Jie
LI Ji-jin
HU Chun-hua
Abstract:Objective To evaluate the influence of Simvastatin with Breviscapine treatment on patients with Coronary Heart Disease and study the changes of hemorheology and Lipoperoxides ( LPO) and Superoxide dismutase ( SOD) .Methods 140 patients were randomly divided into the observation group(Simvastatin with Xueshuantong) and the control group(Simvastatin),the hemorheology,LPO level and SOD level before and after treatment 14 days were detected .Results The total effective rate of the observation group was 97.1%,and the total effective rate of the control group was 75.7%,there was asignificant difference in the two groups ( P<0.05 );the observation group were close to normal levels and that of the control group were only improved ;LPO level reduced and SOD level rose clearly ( P<0.05 ) and there was no improvement in the control group .Conclusion Simvastatin with Breviscapine treatment on patients with Coronary Heart Dis-ease could improve the hemorheology ,reduce the level of LPO , rise the level of the SOD ,and get outstanding clinical efficacy .
Keywords:BreviscapineSimvastatinCoronary Heart DiseaseHemorheologyLipoperoxidesSuperoxide dismutase
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:2( 787-788 )
