Influence of the Level of IL-6, TNF-a and Sputum LTs of Ciclesonide
Abstract：Objective To explore the level of IL-6, TNF-a and sputum LTs of ciclesonide combined montelukast in the treatment ofasthma.Methods 200patientswithacuteexacerbationofasthmawererandomlydividedintotheexperimentalgroup(100cases)and control group ( 100 cases ).The control group were treated with ciclesonide ,and the experimental group were treatd with ciclesonide com-binedmontelukast.Allpatientsweretreatedfortwoweeks.Results 91patientswithclinicalcontrolintheexperimentalgroup,and78pa-tients with clinical control in the control group (P<0.05),the IL-6, TNF-a and sputum LTs level were decreased significantly (P<0.05),and the experimental group had higher degree of decline.Conclusion Ciclesonide combined montelukast may reduce IL -6, TNF-a and sputum LTs levels in the treatment of serum.
Keywords：AsthmaCiclesonideMontelukastInterleukin-6LTsTNF-a
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 779-780 )