Mechanism Research of the Effect of Kaiso and p120 ctn in Bladder Transitional Cell Carcinoma
LIANG Kai
LU De-xiang
Abstract：Objective To explore the mechanism of Kaiso and p120ctn in bladder transitional cell carcinoma (BTCC).Methods The expression of Kaiso and p120ctn were detected in 82 patients with BTCC and 29 normal bladder mucosa tissues by Western -blot.Results The expression level of p120ctn in BTCC was lower than that in the normal group.The expression level of Kaiso in normal bladder mucosa tissues was significantly lower than that in BTCC.The expression level of p 120 ctn in normal bladder mucosa tissues was significantly higher than that in BTCC.The expression of p120ctn was significantly negatively correlated to the expression of Kaiso in urothelial carcinoma of the bladder and normal bladder mucosa (rs=-0.779,P<0.05).Conclusion Kaiso and p120ctn are closely related to the occurrence , clini-cal stage of urothelial carcinoma of the BTCC , which may be new targets for cancer therapy.
Keywords：Kaisop120 ctnBladder neoplasm
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 753-755 )