Clinical Significance of Serum C Peptide and Glycosylated Hemoglobin Combined Examination of in the Diagnosis of Diabetes
HUANG Cai-yun
ZHENG Rui-chun
Abstract：Objective To investigate the serum C peptide combined with glycosylated hemoglobin in the diagnosis of diabetes .Methods Selecting 84 patients of diabetes mellitus during March , 2011 and December , 2012 , of which patients with simple type 2 diabetes as DM group, 28 patients with diabetic nephropathy as diabetic nephropathy group , and 30 health adults in the hospital in physical examination personnel examination center during the same period as control group .Detecting HbA1c, fasting blood glucose (FBG), 2h glucose, C pep-tide and other related indicators after meal .Results (1) DM group, diabetic nephropathy group , serum HbA1c, FBG, 2h postprandial blood glucose were significantly higher than those in the control group , and the serum C peptide levels were significantly lower than those in the control group (P<0.05).(2) Diabetic nephropathy group HbA1c was significantly higher than that in DM group , and C peptide levels were significantly lower than those in the control group (P<0.05).(3)The HbA1c was positively correlated with FBG (r=0.443, P<0. 05), and negatively correlated with C peptide (r=-0.628, P<0.05).Conclusion Diabetes in patients with HbA1c and the level of se-rum C peptide are abnormal .The result can reflect the insulin secretion function and disease severity index .The combination of the two tests has a certain value in diagnosis of diabetic nephropathy .
Keywords：DiabetesDiagnosisC peptideHbA1c
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 666-668 )